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The neuroprotective effects of the ketogenic diet further extend to synaptic plasticity regulation: by increasing -hydroxybutyrate (BHB) levels, it directly activates the ERK/CREB signaling pathway in the hippocampus, promoting brain-derived neurotrophic factor (BDNF) synthesis (especially in females) to restore impaired long-term potentiation (LTP) in Alzheimers model mice

doi:10.2174/187152009789056895 Zhao GS, Wang XB (2006) Advance in antitumor agents targeting glutathione-S-transferase

And they reported vitamin B12 supplementation accelerated tissue repair in the mouse model of ulcerative colitis

Veal, E.A., Day, A.M

In addition to its barrier-sealing effects, L-Glutamine directly influences immune cell behavior