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Appetite and the ghrelin pathway: where ipamorelin diverges from native ghrelin Native ghrelin activates hypothalamic circuits that drive appetite and energy homeostasis alongside its GH-releasing function
10.1126/science.3798106 Science

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We also provide evidence that parkins modulation of the cytosolic redox state impacts mitochondrial function, demonstrated here as an endogenous parkin-dependent change in the activities of two redox-sensitive, mitochondrial enzymes, Aco2 and mtCK
