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Conversely, WT-Bcr-Abl cells after treatment with N-Acetyl-Cysteine (NAC), a GSH precursor that increased the cellular GSH level, exhibited not only increased lengths of replication tracks but also insensitive to JMF4073 (Fig

10.1038/s41572-018-0041-4

From these considerations, it should be appreciated that the critical molecule is succinyl-CoA, carrying the high-energy thioester bond that can be used to generate ATP by mtSLP

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