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The EXTRIP workgroup performed a systematic review on the use of extracorporeal treatment in VPA toxicity

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Although reports on other treatment effects have been published, interventions for which morphological data are available include primarily restoration of normoglycemia by pancreas (or islet) transplantation and polyol pathway blockade by aldose reductase inhibition

Some studies suggest that ALC may have antidepressant properties, making it a potential natural alternative or complement to traditional depression treatments

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