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Abstract Autophagy is a multi-step catabolic process that delivers cellular components to lysosomes for degradation and recycling

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Thus, the enzymatic activity of protein phosphatase 2A (PP2A), a specific phosphatase for -syn, is inhibited, leading to the sustained induction of -Syn p-S129

Importantly, pharmacological GCL inhibition hindered lymphoma growth in female -MYC mice, suggesting that this treatment holds promise as a therapeutic strategy for female lymphoma/leukemia patients.

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