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1 Smaller amounts of GLP-1 are also produced by neurons in the nucleus tractus solitarius (NTS) of the brainstem, thus highlighting its dual role in both peripheral and central metabolic regulation

These expert disclosure deadlines are actively moving forward in early 2026

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The hippocampus underpins memory formation, the prefrontal cortex governs executive function and attention, and the hypothalamus integrates energy status with neuroendocrine signalingfunctions that are progressively disrupted early in neurodegenerative disease

The 2 result did not identify any high heterogeneity in the network, and most comparisons were low or low-moderate levels of heterogeneity (appendix 5)