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Monitor Blood Sugar Levels : If you have diabetes, regularly monitor your blood sugar levels to understand how different foods and activities affect them

This mouse line was originally developed by crossing humanized Glp-1r knockin mice (105) with MIP-Cre/ERT mice (106), both of which are on a C57BL/6 background

Menopausal status did not meaningfully alter treatment response, as seen here: What we know about hormone therapy and weight-loss response Menopausal hormone therapy is not indicated for weight loss

But these options arent as easily removed if at all

The outcome data itself, however, is not ambiguous: at the top doses, tirzepatide went further