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Two groups of healthy Control participants were recruited locally by public advertisement and selected to match the patient groups (site-wise) for age, sex, and parental occupation using the National Statistics Socio-economic classification (NS-SEC), 5-class self-coded method [20]

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Local overexpression of these genes in the mouse brain resulted in increased anxiety-like behaviour, while local inhibition of glyoxalase 1 expression by RNA interference decreased the anxiety-like behaviour

Lebers disease is a hereditary optic neuropathy that causes slow painless vision loss