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Supply Chain Disruptions: Challenges in the global supply chain, exacerbated by factors such as the COVID-19 pandemic, manufacturing issues, and regulatory issues have disrupted the production and distribution of these medications

Joint and mobility issues: Extra weight can strain joints, leading to conditions like osteoarthritis

See: FDAs Concerns with Unapproved GLP-1 Drugs Used for Weight Loss In general, patients should be extremely cautious, always consult their care provider, and thoroughly vet any pharmacy they consider for compounded medications

RELATED: The Best Creatine for Women Build Lean Muscle Without the Bulk Stay on top of your hydration, especially if you experience nausea, vomiting, constipation, or diarrhea

Here's a snapshot of major state-level decisions as of early 2026