Tirzepatide (Month 1) 2.5mg
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Description
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Mounjaro is administered once weekly and works through dual hormone pathways
"Triple-hormone-receptor agonist retatrutide for obesityA phase 2 trial." New England Journal of Medicine , 389(6), 514-526
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The apo-form of the GCGR receptor may exist in a closed state as shown by dynamic simulation where the -helix of the ECD is parallel to the plane of the membrane and a conformational change is required to adopt the open glucagon-bound state of GCGR 22
