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This usually happens because the airway narrows or becomes blocked

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The main roles of GLP-1 are stimulation of glucose-dependent insulin secretion, inhibition of postprandial glucagon release, delay of gastric emptying, and induction of pancreatic -cell proliferation [5]

A 2022 review in Nature Metabolism outlined the concept of receptor downregulation following sustained agonist exposure, a well-established pharmacological principle in which the body reduces its sensitivity to, and endogenous production of, a hormone when that hormone is chronically supplied externally

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