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Another placebo-controlled, double-blind, randomized study in 44 men with idiopathic asthenozoospermia found an increase in sperm motility in those given ALCAR alone (3 g/day) or ALCAR (1 g/day) plus L-carnitine (2 g/day) compared to those given L-carnitine alone (2 g/day) or a placebo (113)
Journal of Back and Musculoskeletal Rehabilitation
Among all nutritional cofactors, VC has the greatest effect on the rate of carnitine biosynthesis

What formulation considerations should be kept in mind for Acetyl-L-Carnitine

Furthermore, activation of the nuclear receptor FXR induced the expression of FMO3 and the production of TMAO (Bennett et al., 2013)
