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Description
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Treatment of 24-month-old mice (equivalent to elderly humans) with NNMT inhibitors rescued age-related deficits in muscle stem cell activity

The mammalian sirtuins (Sirt1--Sirt7) participate in a number of cellular and physiological functions such as gene silencing, apoptosis, mitochondrial function, energy homeostasis, and longevity [237].Transgenic mice with overexpression of the sirt1 gene demonstrate decreased lipid-induced inflammation, improved glucose tolerance, and protection from hepatic steatosis when fed a high-fat diet [238]

[2] Heffernan, M., Summers, R

They could interact with other medicines or health issues
