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Description
The physiological effects of PYY are mediated through a family of NPY receptors (termed Y1, Y2, Y3, Y4, and Y5), which are differentially expressed in a wide range of tissue including enterocytes, myenteric and submucosal neurons and extrinsic primary afferent nerve fibers (123)

Source: Daily Mail 5

GI side effects often peak during this transition before gradually improving

The complexity of dose regimens, the patients perception of administration, and fear of injections may affect the rate of commencing injectable treatment

Most Frequently Reported Side Effects Nausea the most common issue, especially during the first weeks of titration
