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6 A tirzepatida o primeiro agonista dual dos receptores de polipeptdeo insulinotrpico dependente de glicose (GIP) e GLP-1, com alta seletividade e afinidade por ambos os receptores humanos

These areas are critically involved in reward-related pathways, and play an important role in motivation, goal-directed behavior as well as processing of different types of reward (Berridge & Robinson, 1998

In other words, this peptide seems to increase exercise ability on a cellular level

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doi: 10.1001/jamainternmed.2025.6112