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& Winther, J
These senescent cells release harmful pro-inflammatory signals, known as the senescence-associated secretory phenotype (SASP), that damage surrounding tissues and disrupt overall organ function
These results highlight that targeting pathways involved in -KG production offers attractive therapeutically opportunities in diseases associated with macrophage malfunction
Metformin: update on mechanisms of action and repurposing potential
Particularly racquet sports like tennis are a risk factor
