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Conventional SUD management relies on integrated behavioral and pharmacological strategies

Its development and progression are tightly linked with metabolic dysregulation and insulin resistance

These medications belong to a class called GLP-1 receptor agonists

Network and pairwise meta-analyses for total stroke of antihyperglycemic drugs Traditional pairwise (upper right side) and network (lower left side) meta-analytic results are depicted for total stroke

Substantial improvement in beta-cell function with initial combination therapy of sitagliptin and metformin in patients with type 2 diabetes after 1 year of treatment