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Because of the addictive nature of nicotine and tobaccos causal relation to pulmonary conditions and cancer, tobacco use history should be documented when clinically relevant and coded appropriately

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This increases the number of individuals requiring medical care overall and, because the elderly often have more severe health problems, the number of individuals requiring more intense care

Researchers need to decide what biomarkers and biofluids are most appropriate for a given study (Table 2)